Our lab explores ion channel regulation of cellular excitability.
We train tomorrow's scientist in the latest biophysical methods to understand how ion channels control physiological processes and how their dysfunction results in disease.
We are located lake-side in the metropolitan setting of downtown Chicago,
Northwestern University, Feinberg School of Medicine, in the
Department of Pharmacology
Our group focuses on developing novel biophysical methodologies to study ion channels.
We specialize in determining their molecular interactions with drugs and during structural conformational changes.
We are interested in channels of several organ systems, including the brain and kidney.
--Some questions we are investigating---
Which ion channels operate in organelles and how can we design cutting-edge probes to determine their function in the cell?
How do ion channels move and how can we exploit new understandings to control disease?